Hair tissue mineral analysis (HTMA) is a non-invasive test that identifies imbalances in essential minerals and hidden exposures to toxic metals like mercury, lead, arsenic, and cadmium. It provides a time-averaged picture of your body’s mineral metabolism and toxic load—crucial for uncovering root causes of mental health conditions, fatigue, and neurological symptoms.
In the Walsh Biotype model, toxic metals account for up to 5% of cases of relentless, treatment-resistant depression. This is a depression that never lifts, day after day, with no reprieve. If you or your clients experience this severe, constant depression, HTMA is essential to rule out toxic metal overload as a contributing factor.
Not sure where this fits? See our Pathology Testing Packages & Pathways to choose your starting point → /pathology-testing-packages.

Hair tissue mineral analysis (HTMA) is a non-invasive test that identifies imbalances in essential minerals and hidden exposures to toxic metals like mercury, lead, arsenic, and cadmium. It provides a time-averaged picture of your body’s mineral metabolism and toxic load—crucial for uncovering root causes of mental health conditions, fatigue, and neurological symptoms.
In the Walsh Biotype model, toxic metals account for up to 5% of cases of relentless, treatment-resistant depression. This is a depression that never lifts, day after day, with no reprieve. If you or your clients experience this severe, constant depression, HTMA is essential to rule out toxic metal overload as a contributing factor.
🧬 About Hair Tissue Mineral Analysis (HTMA) (H2)
Hair is a metabolic tissue that records mineral levels over time. Unlike blood, which reflects immediate status, hair captures chronic exposure and body burden of toxic elements and nutrient imbalances.
HTMA can detect:
💡“Toxic metals don’t circulate in blood for long — they hide in tissues. Hair analysis helps us find them”
While the Walsh Biotype model highlights toxic metals as a key contributor in up to 5% of relentless, treatment-resistant depression cases, Dr. James Greenblatt further emphasizes the broader neurological impact of toxic metal accumulation and mineral imbalances.
Dr. Greenblatt teaches that toxic metals—such as mercury, lead, and arsenic—can silently disrupt neurotransmitter synthesis, mitochondrial energy production, and antioxidant defenses, leading to a wide range of psychiatric symptoms beyond depression, including:
Where blood tests fall short, HTMA reveals the long-term tissue burden of toxins and functional mineral patterns that affect brain health. Mineral ratios such as:
For practitioners, HTMA becomes a biochemical roadmap to uncover obstacles that labs like blood and urine panels often miss.






Toxic Metals
Essential Nutrient Minerals
Biochemical Ratios & Patterns
🧠 These mineral patterns can reflect detoxification issues, adrenal burnout, and hidden toxic burdens.
What’s Included in Your Kit:
1️⃣ Prepare the Kit & Area
2️⃣ Cutting the Hair Sample
3️⃣ Measuring the Sample Amount
4️⃣ Packing the Sample
5️⃣ Filling Out the Requisition Form
6️⃣ ✉️ Mailing the Sample
💡 Important Collection Facts:
⚠️ Common Mistakes to Avoid:
💡”Relentless, treatment-resistant depression is often biochemical. HTMA helps us rule out the hidden burden of toxic metals”
I’m the practitioner behind BalanSoul. In 15 minutes we’ll map your best next step what to test (and what not to), likely costs/timing, and how it links to your mental health goals.